Exploration of Novel Therapeutic Strategies for the Treatment of Diabetes Mellitus

Abstract

Diabetes mellitus (DM) is a disorder in which the body does not produce enough or respond to insulin normally, resulting in an abnormal increase in blood glucose levels. 90% of diabetes cases in pregnant women are gestational diabetes mellitus (GDM). It is known that fluctuations in the level of glucose and its irregularity led to disturbances in the health of both mother and fetus.The therapeutic strategies and options for the treatment of gestational diabetes are highlighted in this review. We havereviewed medicinal plants used in the treatment of gestational diabetes. Literature review indicates that medicinal plants are effective in treating osteoarthritis and have been clinically and scientifically proven. Natural medicines have been the subject of chemical studies and many plants are the subject of clinical trials. Their results are remarkable and significant. However, scientific exploration for bioactive constituents is becoming increasingly important and their mechanisms of actions to treat GDM are still ongoing.